The right message, the right patient, the right moment.
AXIFI identifies which patients need outreach, personalizes the channel and message, and automates follow-through — all without adding headcount to your front desk.
Built on the Synaptis trust layerHIPAASOC 2 Type IIFDA 21 CFR Part 11Trust Center
Generic reminders do not change patient behavior.
Health systems send millions of appointment reminders and care gap notices every year. Most are ignored. Patients have different preferences, literacy levels, and life circumstances. A 75-year-old managing CHF needs different outreach than a 32-year-old who missed a colonoscopy referral. One-size-fits-all messaging is costing you appointments, quality scores, and patient outcomes.
- Average no-show rate in US ambulatory care: 18–23%
- Care gap closure rates average 34% with templated outreach; 61% with personalized AI outreach
- Patients with chronic conditions see 40% higher engagement when outreach matches their channel preference
- Every unfilled appointment slot costs a primary care practice $100–$200 in direct lost revenue
Understand each patient. Reach them where they are.
Population stratification
AXIFI segments your attributed population by risk tier, care gap type, preferred channel, and likelihood to engage. Stratification updates nightly from your EHR.
Personalized message generation
Each outreach message is generated for the individual patient — reading level, language, channel (SMS, voice, email, portal), and time-of-day preference — by the AXIFI engagement agent.
Automated follow-through
AXIFI handles scheduling links, reminders, no-show recovery, and escalation to a human coordinator when needed. No staff touch until the patient is confirmed.
Outcomes tracking
AXIFI closes the loop: did the patient schedule? Did they show? Was the care gap addressed? Results feed back into the stratification model to improve future outreach.
More patients seen. Fewer gaps in care.
Reduction in no-show rate
primary care, 90-day post-deployment
Increase in care gap closure rate
vs. pre-AXIFI baseline
Patient response rate to AI outreach
vs. 22% industry average
Care gap closure rate by outreach type (%)
What is inside Patient Engagement.
Population stratification engine
Risk-tiers your attributed population nightly. Prioritizes outreach by impact — highest-risk patients with open care gaps surface first.
AI message personalization
Generates outreach in the patient's language, at their reading level, through their preferred channel. Channel preference learned from response history.
Automated scheduling
Deep-linked scheduling integrations let patients book directly from the outreach message. No hold time. No phone tree.
Engagement analytics
Campaign dashboards show open rates, response rates, scheduling conversions, and care gap closure by program, provider, and patient segment.

Works with your existing patient communication stack.
- EHR / population health
- Epic MyChart
- Cerner HealtheIntent
- Arcadia
- Azara Healthcare
- Innovaccer
- Outreach channel
- SMS (TCPA-compliant)
- Voice (IVR + AI voice)
- Patient portal secure message
- Scheduling
- Epic Cadence
- Zocdoc
- Klara
- Relatient
- Direct EHR scheduling API
- Translation
- Spanish
- Mandarin
- Vietnamese
- Haitian Creole
- Arabic
- +40 more via AXIFI language layer
Common questions.
Ready to deploy Patient Engagement in your environment?
See how Synaptis fits into your stack — no generic demos, just your workflow.